pip is the default, poetry adds a lockfile and build system, uv is a 10-100x faster replacement for pip.

Comparison¶

• pip: Built-in, simple, no native lockfile
• poetry: Lockfile, dependency resolution, build & publish
• uv: Rust-based, extremely fast, drop-in pip replacement

uv — Recommended for 2025+¶

pip vs poetry vs uv — Python Dependency Management¶

uv init myproject cd myproject

Add dependencies¶

uv add flask sqlalchemy uv add –dev pytest ruff

Sync (install)¶

uv sync

Run¶

uv run python main.py uv run pytest

Key Takeaway¶

uv for new projects (speed + lockfile). poetry for publishing to PyPI. pip only for simple scripts.